服务项目(Service Items)

周期（月）

Time(months)

多抗方案

polyclone

杂交瘤/单抗方案Hybridoma/Mmonoclone

模型动物构建

Animal Model Construction

基因敲除载体设计与构建

Plasmid construction

6~8

√

√

√

√

Crisper/Cas9技术靶基因敲除

Target Gene Knock out or Cut off by Crisper/Cas9

√

√

√

√

胚胎注射与筛选移植

Screening embryos injected with transplant

√

√

√

√

子代鉴定与扩繁保种

Progeny identification and propagation of conservation

√

√

√

√

分子改造与偶联 

Molecular design \ convertion \conjugation

多肽设计

Peptide design

~2

√

√

多肽或蛋白合成

Peptide or protein synthesis

√

免疫阶段Immunization

免疫2只小鼠

Immunized 2 mice

~8

√

√

免疫5只小鼠

Immunized 5 mice

√

√

ELISA检测

Elisa detection

√

√

√

√

细胞融合与筛选

Fusion & Screening

1.5

√

√

亚克隆阶段

subcloning

1

√

√

腹水生产（5只小鼠）                    

Ascites production (Injection on 5 mice)

1

√

√

纯化与检测

Purification and detection

亲和纯化

Affinity purification

~1

√

√

√

√

特异性亲和纯化 

Antigen specific affinity purification

总周期（月）        Total lead time(months)

8~10

8~12